@Doc
I agree with the previous comments. You can definitely open more than one copy of Outlook at once.
What you can't do is have two different versions of Outlook installed on the same PC.
I have both Office 2010 & 365 installed on this PC and have two versions of Access, Word, Excel etc but it won't let you do that with Outlook
@JohnPapa
Have you looked at the CDO help file yet. This is the relevant part:
View attachment 81982
You need to swop your SendUsing setting from 1 to 2 (or vice versa)
I tried all options without success. Maybe I do not have the correct Port and or Email Server information.